References & Case Studies
Isolator with Laminar Airflow for Product Transfer and Bottle Filling
Customer: Bioveta (Isolator IZV11127)
Land: Czech Republic
Year: 2024
Isolator Purpose: Isolator with laminar airflow is used for product transfer using a peristaltic pump, connecting loops via tri-clamp fittings, and filling bottles.
- The IZV11127 isolator with laminar airflow is used for product transfer using a peristaltic pump, connecting loops via tri-clamp fittings, and filling bottles. The purpose of the isolator is to ensure operator safety during the handling of hazardous materials.
- The isolator operates under standard atmospheric conditions.
- The equipment is fitted with an integrated hydrogen peroxide vapor generator designed to evaporate a liquid H₂O₂ solution and subsequently deliver hydrogen peroxide vapor at the required concentration into the isolator chambers using compressed air. This process provides surface decontamination of the loaded material and achieves a 6-log reduction (10⁻⁶) in biological contamination. The isolator cannot be opened during the decontamination process.
- The equipment is equipped with a hydrogen peroxide concentration sensor, as well as humidity and temperature sensors. The system is designed as a dual-chamber unit.
- The maximum permissible leakage rate complies with Leakage Class 3 requirements for containment devices in accordance with ČSN EN ISO 14644-7 (ISO 10648-2).
- The equipment operates under negative pressure.
- Control of the pressure differential and internal atmosphere exchange modes is performed electronically via an HMI control panel located on the upper cover on the right-hand side of the isolator. A status beacon providing the user with a quick overview of operating and fault conditions is mounted on the upper structure of chamber C1.
- Room air is supplied to the isolator through a pre-filter, an inlet fan, and HEPA filters located inside the isolator chambers. Neither air temperature nor relative humidity is controlled. Air from the isolator is exhausted through a pair of HEPA filters to a dedicated HVAC exhaust system.
